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A cancer drug boosts levels of a key protein red in mice lacking

A cancer drug boosts levels of a key protein red in mice lacking

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A cancer drug boosts levels of a key protein (red) in mice lacking SHANK3

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Scientists reveal new details of how a naturally occurring hormone can boost memory in aging mice

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(a) CREB (green) and TH (red) staining in locus coeruleus of control and Creb1DBHCre/Crem −/− mutant mouse.

CT26-FL3 (RFP/Luc) cells were inoculated into the mouse cecum wall, and the tumor ...

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Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer | Scientific Reports

Researchers identify 'Achilles' heel' of PTEN that helps drive prostate cancer progression

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In vitro and in vivo controlled release of drug using layered double hydroxides and its effects. a In vitro drug release profiles for drug intercalated ...

Mice were immunized via i.n. or i.m. routes (n=4 per group) with STxB-E7+α-GalCer (prime D0) and boosted at D14 with STxB-E7. At day 21, the BALs from the ...

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Metastatic human prostate cancer cells transplanted into a mouse ...

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a cBioportal analysis of pro-survival Bcl-2 family member gDNA and mRNA level using TCGA Breast Invasive Carcinoma data set. Unaltered cases not shown, ...

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Targets for transcription therapy. In normal cells (a), proliferation, differentiation and survival stimuli are transduced at the transcription level ...

A breast tumor (green and blue) with a cluster of slow-growing treatment-resistant cells (red).

In 1900, 1 of every 33 deaths was due to cancer. In 2007, over 1 of every 4 deaths was due to cancer. North America's incidence of cancer is staggering.

(a) Immobility of control, Creb1DBHCre, and Creb1DBHCre/Crem−/− male mice on the TST after desipramine treatment (single dose, ...

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Proteins in tissue

Development of drugs targeting cell adhesion

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(A) Western blot of ADAM9 and CDCP1 in Bm7-shGFP (control) and -shADAM9 cells. ADAM9 proteins were detected in non-reducing gels using the antibody from R&D ...

Inhibition of AR enhances the sensitivity of colon cancer cells to DOX: MTT cell viability assay showing the effect of chemotherapeutic drug DOX (0.1–1 μM) ...

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CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance | Molecular Cancer Therapeutics

CD44+ OCSC1s but not their progeny CD44− OCC1s possess cancer stem cell properties. (a) Schematic representation of the isolation of OCSCs and OCCs.

IGF-1

Do High-Protein Diets Cause Kidney Disease and Cancer?

Targeting Homologous Recombination by Pharmacological Inhibitors Enhances the Killing Response of Glioblastoma Cells Treated with Alkylating Drugs ...

Ketogenic Diet Improves Response To Cancer Drug In Mice, But Alone May Accelerate Cancer

Lack of blood or loss of blood may result in diseases like anemia. Ifanemia is left untreated for a long period of time it may cause damage to your brain ...

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Natural protein could beat insulin resistance and provide a new treatment for diabetes

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PRIMARY VERSUS ACQUIRED RESISTANCE: Cancer cells can evolve ways to evade a drug's attack, or they may already be resistant prior to treatment.

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Int J Biol Sci Image

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High-Tech Drug Design

a Immunohistochemical analysis showing MCL-1 protein expression at different stages of mammary tumorigenesis (written above image) evident within a single ...

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Schematic presentation of the actions, through which the antitumor effects of vanadium are exerted (

Researchers identify 'Achilles' heel' of PTEN that helps drive prostate cancer progression

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Number of publications regarding: cancer cell lines as models for cancer research (blue line

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Protocol scheme for phagocytosis quantification.

Red meat has been designated as a 'probable cause' of cancer

Ablation of Btg1 causes a strong increase of proliferating GCPs in the EGL, accompanied by

10 Essential Facts About Metabolism and Weight Loss

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Chemotherapy can be taken as an oral tablet or through an intravenous drip

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... opportunity for cancer treatment. Graphical Abstract

Human vs mouse C9orf72 protein alignment.

Salmon contains nutrients that help the body get the most energy from the other foods you

Depriving tumours of asparagine, which is abundant in asparagus, appears to prevent tumours spreading

U.S. Cancer Death Rates Decline Overall, but Some Cancers Are on the Rise

Weekly Dose: Keytruda may be a miracle cancer drug, but can those who need it afford it?

This mouse was involved in the study which identified serotonin receptor HTR7 as a key mediator of chronic itch.

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Elevated hematocrit enhances platelet accumulation following vascular injury | Blood Journal

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Hemoglobin levels (g/dL) for Case 2, 27-year-old

The brain of a 10-month-old mouse with Alzheimer's disease (left) is full of amyloid plaques (red) surrounded by activated microglial cells (green).

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Tamoxifen-side-effects

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Aloke Finn, MD and colleagues show that mice lacking the protein CD163 show an enhanced repair response to ischemic injury.

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While the above activities may directly affect IGF-1 levels, turning on the regulator of our ROS defense system provides some valuable lessons.

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The resistance to oxidative stress is shut off by excessive amounts of insulin and IGF-1,90 and as a result, oxidative and free radical damage occurs, ...

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FIG. 3.

In red are promising treatments for eradication parasite/cancer cells. Full lines indicate direct increase/activation effects and dashed ...

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A cancer drug boosts levels of a key protein (red) in mice lacking SHANK3

This is ...

Scientists reveal new details of how a naturally occurring hormone can boost memory in aging mice

A network integration approach for drug-target interaction prediction and computational drug repositioning from heterogeneous information | Nature ...

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(a) CREB (green) and TH (red) staining in locus coeruleus of control and Creb1DBHCre/Crem −/− mutant mouse.

Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer | Scientific Reports

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Tumor Biology Study Suggests Promising New Route to Cancer Drug Development

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MCL-1 is a prognostic indicator and drug target in breast cancer | Cell Death & Disease

The Ideal Treatment for every Cancer Patient (JPG, 1.5 MB)

In vitro and in vivo controlled release of drug using layered double hydroxides and its effects. a In vitro drug release profiles for drug intercalated ...

In 1900, 1 of every 33 deaths was due to cancer. In 2007, over 1 of every 4 deaths was due to cancer. North America's incidence of cancer is staggering.

A breast tumor (green and blue) with a cluster of slow-growing treatment-resistant cells (red).

Metastatic human prostate cancer cells transplanted into a mouse ...

(a) Immobility of control, Creb1DBHCre, and Creb1DBHCre/Crem−/− male mice on the TST after desipramine treatment (single dose, ...

Mice were immunized via i.n. or i.m. routes (n=4 per group) with STxB-E7+α-GalCer (prime D0) and boosted at D14 with STxB-E7. At day 21, the BALs from the ...

Shown is ...

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Infographic: Enhancing Chemotherapy

Breast cancers enhance their growth by recruiting cells from bone marrow

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Proteins in tissue

Development of drugs targeting cell adhesion

a, BRAF mutant melanoma cells treated with 1 μM dabrafenib (451Lu cells) or 0.5 μM dabrafenib + 0.05 μM trametinib (A375, A101D and Mel888 cells) and ...

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p53 protein aggregation promotes platinum resistance in ovarian cancer | Oncogene

breast cancer

CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance | Molecular Cancer Therapeutics

IGF-1

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Natural protein could beat insulin resistance and provide a new treatment for diabetes

blood

Protein-Based Therapeutic Killing for Cancer Therapies: Trends in Biotechnology

Ill Effects: How Soda Pop Consumption Affects Your Body

Expansion of the SVZ in mice lacking Nfix. Coronal sections of P10 Nfix +/

Lack of blood or loss of blood may result in diseases like anemia. Ifanemia is left untreated for a long period of time it may cause damage to your brain ...

Do High-Protein Diets Cause Kidney Disease and Cancer?

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Lung metastasis development is inhibited in mice lacking

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High-Tech Drug Design

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(A) Western blot of ADAM9 and CDCP1 in Bm7-shGFP (control) and -shADAM9 cells. ADAM9 proteins were detected in non-reducing gels using the antibody from R&D ...

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Figure 1 Effect of curcumin on various cellular pathways of different types of cancer.

Schematic presentation of the actions, through which the antitumor effects of vanadium are exerted (

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Schematic representation of mechanisms of action and resistance biomarkers in main colorectal cancer chemotherapies.

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Fig. 2.

Chronotherapy Could Make Cancer Treatments More Effective, Here

Number of publications regarding: cancer cell lines as models for cancer research (blue line

The cell viability of colon 26 cells 4 h after treatment with 5-FU,

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Red meat has been designated as a 'probable cause' of cancer

10 Essential Facts About Metabolism and Weight Loss

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Grapefruit Juice and Medicine May Not Mix (6774935740).jpg

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... opportunity for cancer treatment. Graphical Abstract

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Chemotherapy can be taken as an oral tablet or through an intravenous drip

Depriving tumours of asparagine, which is abundant in asparagus, appears to prevent tumours spreading

U.S. Cancer Death Rates Decline Overall, but Some Cancers Are on the Rise

Cellular signalling processes in which arginine methylation has integral roles.Protein arginine methyltransferases (PRMTs

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DSC-TB0313_01

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Elevated hematocrit enhances platelet accumulation following vascular injury | Blood Journal

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Weekly Dose: Keytruda may be a miracle cancer drug, but can those who need it afford it?

Fig. 1.

Hemoglobin levels (g/dL) for Case 2, 27-year-old

Polyoma virus middle T cancer cells express activated STAT3 and FR. Immunofluorescent histochemical staining of

Intrinsic anti-tumor and anti-angiogenic functions of type I interferons.

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Tamoxifen-side-effects

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While the above activities may directly affect IGF-1 levels, turning on the regulator of our ROS defense system provides some valuable lessons.

Aloke Finn, MD and colleagues show that mice lacking the protein CD163 show an enhanced repair response to ischemic injury.

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Schematic of (A) passive (via the EPR effect) and (B)

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